Carys Cox and Hannah Dallavalle return to Wales’ backline for the Six Nations trip to Ireland on Saturday (18:30 BST).
Cox missed the defeats by France and England after picking up a knock in training, while Dallavalle was a late withdrawal against the Red Roses.
Cox slots back into midfield alongside Courtney Keight, while Dallavalle, usually a centre herself, moves out to the wing in place of Seren Singleton.
Georgia Evans is the third starting change, taking her place in the second row in place of the injured Gwen Crabb.
It will be Evans’ first start of the campaign and she is partnered by Branwen Metcalfe who trades positions with Jorja Aiono in the back row.
Nikita Prothero is set for a debut off the bench, while Natalia John could win her 50th cap.
Bethan Lewis will lead the side out at Affidea Stadium, with Kate Williams ruled out of the rest of the tournament with a leg injury.