Despite losing their previous eight Six Nations matches, Wales came into the game with confidence after they registered a record four tries against world champions England in their last outing.
They started stronger in Belfast, but Wafer gave Ireland the lead against the run of play when the back row’s persistence paid off and she forced her way over the line before Dannah O’Brien added a challenging extra two.
Wales looked to respond quickly with a huge tackle from Parsons denying Hannah Dallavalle after Carys Cox had taken advantage of a mix-up and fed the ball through.
The visitors kept pushing and registered their first try when Georgia Evans dived over from close range and Keira Bevan was able to convert to level the match.
A double movement denied Cliodhna Moloney-MacDonald after she had powered her way over as the home side, buoyed by a vocal crowd, began to settle.
Wafer then turned provider, shrugging off multiple white shirts before a superb offload to Parsons, who raced down the right wing to restore Ireland’s lead.
They then struck a hammer blow just before the break as, opting to play on with clock in the red, Ireland were rewarded for their persistence as they added their third try when Hogan crossed after sustained pressure from a ruck.
After the restart, a television match official [TMO] check confirmed Moloney-MacDonald’s kick out at Evans warranted a yellow card.
Wales were unable to take advantage of having an extra player and it was soon 14-players apiece for a period as Jasmine Joyce was shown a yellow card for placing her hands on the ground when bringing Eve Higgins down.
As the hour mark approached, Aoife Dalton and Linda Djougang linked up and fed the ball to Wafer to cross to secure the bonus point.
Bemand then turned to his bench and made a flurry of changes which added energy to their play.
Replacement Jones thought she had added Ireland’s fifth shortly after her introduction, only for her effort to be ruled out after a TMO review.
Joyce added Wales’ second try in the final five minutes as she held off Parsons and stretched to ground the ball.
Ireland did land a fifth try in the final seconds as Hogan bundled over from close range, with O’Brien able to convert for a fourth time.